Dr. Álvaro Castells García
MEET THE FELLOW
Alvaro Castells Graduated in Biochemistry and Biomedical Sciences (University of Valencia, 2014) and holds a Ph.D. in Biomedicine from Pompeu Fabra University (2019). During his PhD, he worked on the Reprogramming and Regeneration lab in the Centre for Genomic Regulation.
From there, he was hired as an Associate Researcher by the Guangzhou Regenerative Medicine and Health Guangdong Laboratory (GRMH-GDL) (2019-2022) and as an Associate Researcher in the Guangdong Provincial People’s Hospital, Guangzhou, China (2022-2024). Since 2024, he has been working at IMDEA Nanociencia as a MSCA-IDEAL postdoctoral researcher, in the Prof. Cristina Flors lab.
Alvaro´s expertise is centered on the application of Advanced Microscopy Methods to understanding the relation between chromatin structure and cell function. He has a deep understanding of Single Molecule Localization Microscopy and chromatin architecture.
Relevant publications
Castells-Garcia, A., Ed-daoui, I., González-Almela, E., Vicario, C., Ottestrom, J., Lakadamyali, M., Neguembor, M.V., and Cosma, Maria P. (2021). Super resolution microscopy reveals how elongating RNA polymerase II and nascent RNA interact with nucleosome clutches. Nucleic acids research.
Otterstrom, J., Castells-Garcia, A., Vicario, C., Gomez-Garcia, P.A., Cosma, M.P., and Lakadamyali, M. (2019). Super-resolution microscopy reveals how histone tail acetylation affects DNA compaction within nucleosomes in vivo. Nucleic acids research 47, 8470-8484.